Inhibition of glutamate uptake by Tx3-4 is dependent on the redox state of cysteine residues.

@article{Reis2000InhibitionOG,
  title={Inhibition of glutamate uptake by Tx3-4 is dependent on the redox state of cysteine residues.},
  author={Helton Jos{\'e} dos Reis and Marcus Vin{\'i}cius Gomez and Evanguedes Kalapothakis and Carlos A. R. Diniz and Marta do Nascimento Cordeiro and Marco A M Prado and Marco Aur{\'e}lio Romano-Silva},
  journal={Neuroreport},
  year={2000},
  volume={11 10},
  pages={2191-4}
}
Glutamate transporters are essential for the homeostasis of glutamate and normal function of glutamatergic synapses. Their function was shown to be regulated by redox agents and dimerizations that involves redox changes of cysteine residues. Peptide neurotoxins are also known to be rich in cysteine residues that contribute to their activity and stability… CONTINUE READING