• Corpus ID: 4842915

Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.

@article{Snchez2001InhibitionOG,
  title={Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.},
  author={Cristina S{\'a}nchez and Mar{\'i}a L. de Ceballos and Teresa G{\'o}mez del Pulgar and Daniel Rueda and C{\'e}sar Corbacho and Guillermo Velasco and Ismael Galve-Roperh and John W Huffman and Santiago Ram{\'o}n y. Cajal and Manuel Guzm{\'a}n},
  journal={Cancer research},
  year={2001},
  volume={61 15},
  pages={
          5784-9
        }
}
The development of new therapeutic strategies is essential for the management of gliomas, one of the most malignant forms of cancer. We have shown previously that the growth of the rat glioma C6 cell line is inhibited by psychoactive cannabinoids (I. Galve-Roperh et al., Nat. Med., 6: 313-319, 2000). These compounds act on the brain and some other organs through the widely expressed CB(1) receptor. By contrast, the other cannabinoid receptor subtype, the CB(2) receptor, shows a much more… 

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