Inhibition of gene expression of heparin-binding epidermal growth factor-like growth factor by extracellular superoxide dismutase in rat aortic smooth muscle cells.

Abstract

Both extracellular superoxide dismutase (EC-SOD) and heparin binding EGF like growth factor (HB-EGF) are produced in smooth muscle cells of the arterial wall, and are thought to play pathological roles in atherosclerosis with heparin binding characteristics. EC-SOD treatment clearly reduced the H2O2 induced expression of HB-EGF in rat aortic smooth muscle… (More)

Topics

Cite this paper

@article{Nishimura2006InhibitionOG, title={Inhibition of gene expression of heparin-binding epidermal growth factor-like growth factor by extracellular superoxide dismutase in rat aortic smooth muscle cells.}, author={Masashi Nishimura and Tomomi Ookawara and Hironobu Eguchi and Noriko Fujiwara and Daisaku Yoshihara and Jun Yasuda and Osamu Mimura and Keiichiro Suzuki}, journal={Free radical research}, year={2006}, volume={40 6}, pages={589-95} }