Inhibition of gene expression by ribozymes.


RNA enzymes, or ribozymes, can be defined as RNA molecules that promote a variety of reactions involving RNA and DNA molecules. These include site-specific cleavage, ligation, polymerization, and phosphoryl exchange (1). The use of ribozymes for medical therapy was recognized soon after RNA catalysis was discovered in the early 1980s (2). Three broad… (More)
DOI: 10.1385/1-59259-085-3:105


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