Inhibition of gastrin gene expression by somatostatin.
@article{Karnik1989InhibitionOG, title={Inhibition of gastrin gene expression by somatostatin.}, author={P. S. Karnik and S. J. Monahan and M. Wolfe}, journal={The Journal of clinical investigation}, year={1989}, volume={83 2}, pages={ 367-72 } }
Previous studies performed in this laboratory have demonstrated somatostatin-containing cells in close proximity to gastrin cells in antral mucosa and have shown that somatostatin exerts a local regulatory effect on gastrin release. The present studies were directed to determine whether the effects of somatostatin on the antral gastrin cell involve pretranslational events. The effects of somatostatin on gastrin mRNA were determined by dot blot hybridization using a gastrin antisense RNA probe… Expand
69 Citations
Somatostatin inhibition of gastrin gene expression: involvement of pertussis toxin-sensitive and -insensitive pathways
- Biology, Medicine
- Regulatory Peptides
- 1992
- 7
The effects of peptide histidine isoleucine on antral gastrin and somatostatin
- Biology, Medicine
- Molecular and Cellular Endocrinology
- 1992
- 2
Effects of calcitonin gene-related peptide on somatostatin and gastrin gene expression in rat antrum
- Biology, Medicine
- Regulatory Peptides
- 1998
- 14
Studies of Regulation of Gastrin Synthesis and Post‐translational Processing by Molecular Biology Approaches a
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1990
- 8
Regulation of rat antral gastrin and somatostatin gene expression during starvation and after refeeding.
- Biology, Medicine
- Gastroenterology
- 1991
- 76
Developmental biology of gastrin and somatostatin cells in the antropyloric mucosa of the stomach
- Biology, Medicine
- Microscopy research and technique
- 2000
- 60
Detection of gastrin mRNA in human antral mucosa and digestive endocrine tumors by in situ hybridization: a correlative study with immunocytochemistry and electron microscopy.
- Biology, Medicine
- The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
- 1992
- 14
Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1.
- Biology, Medicine
- American journal of physiology. Gastrointestinal and liver physiology
- 2003
- 45
- PDF
Effects of carbamylcholine chloride on human antral gastrin mRNA levels
- Chemistry, Medicine
- Journal of Gastroenterology
- 2006
Expression of the gastrin gene in the normal human colon and colorectal adenocarcinoma.
- Biology, Medicine
- Cancer research
- 1993
- 66
References
SHOWING 1-10 OF 39 REFERENCES
Inhibition of gastrin release by secretin is mediated by somatostatin in cultured rat antral mucosa.
- Chemistry, Medicine
- The Journal of clinical investigation
- 1983
- 59
- PDF
Postreceptor inhibition of antral gastrin release by somatostatin.
- Chemistry, Medicine
- Gastroenterology
- 1985
- 17
Regulation of growth hormone mRNA and pro-opiomelanocortin mRNA levels by cyclic AMP in rat anterior pituitary cells in culture.
- Chemistry, Medicine
- DNA
- 1986
- 38
Dietary regulation of rat intestinal cholecystokinin gene expression.
- Biology, Medicine
- The Journal of clinical investigation
- 1988
- 43
- PDF
Somatostatin-like immunoreactivity in the glomerulus of rat kidney.
- Chemistry, Medicine
- Kidney international
- 1983
- 26
- PDF
Capillary orientation of rat pancreatic D-cell processes: evidence for endocrine release of somatostatin.
- Biology, Medicine
- The American journal of physiology
- 1985
- 17
Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin
- Biology, Medicine
- Nature
- 1983
- 284
Glucocorticoid stimulation of growth hormone messenger ribonucleic acid levels in GH3 cells is inhibited by calcium but not by somatostatin.
- Biology, Medicine
- Endocrinology
- 1987
- 23
Somatostatin-like immunoreactivity in the retina.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1980
- 140
- PDF