Inhibition of focal adhesion kinase induces apoptosis in human osteosarcoma SAOS-2 cells


Focal adhesion kinase (FAK), a non-receptor tyrosine kinase protein, acts as an early modulator of integrin signaling cascade, regulating basic cellular functions. In transformed cells, unopposed FAK signaling has been considered to promote tumor growth, progression, and metastasis. The aim of this study was to assess the role of focal adhesion kinase in… (More)
DOI: 10.1007/s13277-013-1214-0


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