Inhibition of fibrocyte differentiation by serum amyloid P.

  title={Inhibition of fibrocyte differentiation by serum amyloid P.},
  author={Darrell Pilling and Christopher D Buckley and Mike Salmon and Richard H Gomer},
  journal={Journal of immunology},
  volume={171 10},
Wound healing and the dysregulated events leading to fibrosis both involve the proliferation and differentiation of fibroblasts and the deposition of extracellular matrix. Whether these fibroblasts are locally derived or from a circulating precursor population is unclear. Fibrocytes are a distinct population of fibroblast-like cells derived from peripheral blood monocytes that enter sites of tissue injury to promote angiogenesis and wound healing. We have found that CD14(+) peripheral blood… CONTINUE READING


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Not being the wrong size

  • N. Shamsadeen, D. Scheel-Toellner, C. Buckley, M. Salmon
  • Nat . Rev . Mol . Cell Biol .
  • 2001

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