Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer

Abstract

The alternative splicing of the extracellular domain of fibroblast growth factor receptor (FGFR)-2 generates the IIIb and IIIc isoforms. Expression of FGFR-2 IIIb correlates with vascular endothelial growth factor-A (VEGF-A) expression and venous invasion of pancreatic ductal adenocarcinoma (PDAC). By contrast, FGFR-2 IIIc expression correlates with faster… (More)
DOI: 10.1111/cas.12470

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Cite this paper

@inproceedings{Matsuda2014InhibitionOF, title={Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer}, author={Yoko Matsuda and Hisashi Yoshimura and Taeko Suzuki and Eiji Uchida and Zenya Naito and Toshiyuki Ishiwata}, booktitle={Cancer science}, year={2014} }