Inhibition of endothelial cell thromboresistance by homocysteine.

  title={Inhibition of endothelial cell thromboresistance by homocysteine.},
  author={Q B Ling and Katherine A Hajjar},
  journal={The Journal of nutrition},
  volume={130 2S Suppl},
Homocysteine (HC) is a highly reactive thiol intermediate in amino acid metabolism, which can modify the function of endothelial cells in a myriad of ways. In vitro, homocysteine can inhibit the thromboresistance properties of the endothelial cell by induction of procoagulant factors, inactivation of natural anticoagulant systems, and suppression of… CONTINUE READING