Inhibition of dexamethasone-induced cytochrome P450-mediated mutagenicity and metabolism of aflatoxin B1 by Chinese medicinal herbs.

Abstract

Oldenlandia diffusa (OD) and Scutellaria barbata (SB) have been used in traditional Chinese medicine for treating liver, lung and rectal tumours. We previously showed that they inhibited mutagenesis, DNA binding and metabolism of aflatoxin B1 (AFB1) and benzo(a)pyrene (BaP) bioactivated by Aroclor 1254-induced rat S9. The purpose of this study was to… (More)

Topics

Cite this paper

@article{Wong1993InhibitionOD, title={Inhibition of dexamethasone-induced cytochrome P450-mediated mutagenicity and metabolism of aflatoxin B1 by Chinese medicinal herbs.}, author={Bryan Y. Wong and B H Lau and T. Yamasaki and Robert W. Teel}, journal={European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation}, year={1993}, volume={2 4}, pages={351-6} }