Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin.

@article{Staite1996InhibitionOD,
  title={Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin.},
  author={Nigel D. Staite and James M. Justen and Laurel M. Sly and Arthur L Beaudet and Daniel C. Bullard},
  journal={Blood},
  year={1996},
  volume={88 8},
  pages={2973-9}
}
Leukocyte rolling and emigration in response to inflammatory stimuli appears to involve both E-selectin- and P-selectin-dependent adhesion, which suggests that these molecules have overlapping functions. To clarify their relative contributions in chronic inflammation, we examined delayed-type contact hypersensitivity (DTH) responses in P-selectin, E-selectin, and E-/P-selectin-deficient mice. Oxazolone-induced increases in ear thickness and ear weight were equivalent in wild-type mice and in P… CONTINUE READING
58 Citations
26 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

P - selectin / lCAM - 1 double mutant mice : Acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alve

  • RC Johnson, TN Mayadas, +4 authors DD Wagner
  • J Clin Invest
  • 1995

Similar Papers

Loading similar papers…