Inhibition of cytokine gene transcription by the human recombinant histamine-releasing factor in human T lymphocytes.

@article{Vonakis2003InhibitionOC,
  title={Inhibition of cytokine gene transcription by the human recombinant histamine-releasing factor in human T lymphocytes.},
  author={Becky Marie Vonakis and Rebecca Sora and Jacqueline M. Langdon and Vincenzo Casolaro and Susan M. Macdonald},
  journal={Journal of immunology},
  year={2003},
  volume={171 7},
  pages={
          3742-50
        }
}
  • Becky Marie Vonakis, Rebecca Sora, +2 authors Susan M. Macdonald
  • Published in Journal of immunology 2003
  • Biology, Medicine
  • Human recombinant histamine-releasing factor (HrHRF) preincubation enhances the secretion of histamine, IL-4, and IL-13 from FcepsilonRI-stimulated human basophils. In GM-CSF-primed human eosinophils, HrHRF increases IL-8 production. Our recent experiments were designed to evaluate the effects of HrHRF on human T cell cytokine production. Purified T cells were preincubated with GST-tagged HrHRF, followed by stimulation with PMA and A23187 overnight. A partial inhibition of IL-2 and IL-13… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 16 CITATIONS

    Histamine-Releasing Factor and Immunoglobulins in Asthma and Allergy

    VIEW 1 EXCERPT
    CITES BACKGROUND