Inhibition of cytokine and surface antigen expression in LPS-stimulated murine macrophages by triethylene glycol dimethacrylate.

@article{Eckhardt2009InhibitionOC,
  title={Inhibition of cytokine and surface antigen expression in LPS-stimulated murine macrophages by triethylene glycol dimethacrylate.},
  author={Alexander Eckhardt and Tolga Harorli and Jirakant Limtanyakul and Karl-Anton Hiller and Claudia Bosl and Carola Bolay and F. X. Reichl and Gottfried Schmalz and Helmut Schweikl},
  journal={Biomaterials},
  year={2009},
  volume={30 9},
  pages={
          1665-74
        }
}
Dental resin monomers like triethylene glycol dimethacrylate (TEGDMA) cause a shift in the cellular redox balance which influences redox-sensitive signaling pathways. The immediate response of the innate immune system to inflammatory challenges is controlled by related pathways. Therefore, the influence of TEGDMA on the expression of the pro- and anti-inflammatory cytokines TNF-alpha, IL-6, and IL-10 and surface antigens (CD14, CD40, CD80, CD86, CD54, MHC class I and II) was analyzed in RAW264… CONTINUE READING
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