Inhibition of cyclic AMP efflux by insect pheromones and fatty acids.

Abstract

Avian erythrocytes export cyclic AMP by a means that prostaglandins A1 and A2, but not other eicosanoids, inhibit (EC50 approximately 45 nM). Several insect pheromones and the fatty acyl components of common membrane phospholipids also inhibit cyclic AMP efflux (EC50 approximately 30 microM). The presence of at least one double bond in the acyl chain… (More)

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