Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs

@inproceedings{Khaliq2010InhibitionOC,
  title={Inhibition of core gene of HCV 3a genotype using synthetic and vector derived siRNAs},
  author={Saba Khaliq and S Shah Jahan and Bushra Ijaz and Waqar Ahmad and Sultan Asad and Asim Pervaiz and Baila Samreen and Mahwish Khan and Sajida Hassan},
  booktitle={Virology Journal},
  year={2010}
}
Hepatitis C virus (HCV) is a major causative agent of liver associated diseases throughout the world, with genotype 3a responsible for most of the cases in Pakistan. Due to the limited efficiency of current therapy, RNA interference (RNAi) a novel regulatory and powerful silencing approach for molecular therapeutics through a sequence-specific RNA degradation process represents an alternative option. The current study was purposed to assess and explore the possibility of RNAi to silence the HCV… CONTINUE READING

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