Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes

Abstract

Decay-accelerating factor (DAF), extracted from the stroma of human erythrocytes, was purified to homogeneity and incorporated into the membrane of sheep red cell complement intermediates, where its functional properties were analyzed. Incorporation of DAF into the cell membranes was temperature dependent, took place on pronase- or trypsin-treated… (More)

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