Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.

  title={Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.},
  author={Barbara Romano and F. Borrelli and E. Pagano and M. G. Cascio and R. Pertwee and A. Izzo},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={21 5},
  • Barbara Romano, F. Borrelli, +3 authors A. Izzo
  • Published 2014
  • Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • PURPOSE Colon cancer is a major public health problem. Cannabis-based medicines are useful adjunctive treatments in cancer patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS, i.e. CBD botanical drug substance, on colorectal cancer cell proliferation and in experimental models of colon cancer in vivo. METHODS Proliferation was evaluated in colorectal carcinoma (DLD-1 and HCT116) as well as in… CONTINUE READING
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