Inhibition of collagenase breakdown of equine corneas by tetanus antitoxin, equine serum and acetylcysteine.

@article{Haffner2003InhibitionOC,
  title={Inhibition of collagenase breakdown of equine corneas by tetanus antitoxin, equine serum and acetylcysteine.},
  author={John C Haffner and Kellie A. Fecteau and Hugo Eiler},
  journal={Veterinary ophthalmology},
  year={2003},
  volume={6 1},
  pages={67-72}
}
OBJECTIVE To determine whether tetanus antitoxin, equine serum, and acetylcysteine, which are currently used in the treatment of equine corneal ulcer, inhibit the digestion of equine corneal collagen when exposed to collagenase in vitro. ANIMALS STUDIED Corneas from 40 adult horses. PROCEDURES Sections of equine corneas were incubated with saline, a solution of bacterial collagenase in saline, bacterial collagenase in saline plus equine tetanus antitoxin, bacterial collagenase in saline… CONTINUE READING

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