Inhibition of cold-induced TSH release by benzodiazepines

@article{Camoratto1983InhibitionOC,
  title={Inhibition of cold-induced TSH release by benzodiazepines},
  author={A. M. Camoratto and L. Grandison},
  journal={Brain Research},
  year={1983},
  volume={265},
  pages={339-343}
}
Abstract Diazepam (1–5 mg/kg, i.p.) did not alter basal thyroid-stimulating hormone (TSH) release in rats; however, both diazepam (2 mg/kg, i.p.) and clonazepam (1 mg/kg, i.p.) blocked the 3–5-fold increase in TSH induced by cold exposure. The benzodiazepine antagonist, Ro15-1788 (10 mg/kg, i.p.) was effective in reversing clonazepam inhibition of cold-induced TSH release, but when administered alone had no effect on either basal TSH levels or the rise in TSH following cold exposure. Diazepam… Expand
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