Inhibition of cholesteryl ester deposition in macrophages by calcium entry blockers: an effect dissociable from calcium entry blockade.

@article{Daugherty1987InhibitionOC,
  title={Inhibition of cholesteryl ester deposition in macrophages by calcium entry blockers: an effect dissociable from calcium entry blockade.},
  author={Alan Daugherty and Debra L. Rateri and Gustav Schonfeld and B. E. Sobel},
  journal={British journal of pharmacology},
  year={1987},
  volume={91 1},
  pages={113-8}
}
The effects of calcium entry blockers on stimulated cholesteryl [3H]-oleate deposition in cultured macrophages were characterized in order to elucidate mechanisms underlying possible antiatherosclerotic effects. Stimulation of intracellular cholesteryl [3H]-oleate deposition was initiated by incubation of macrophages with beta-very low density lipoproteins (beta-VLDL). Nifedipine (Class I) markedly reduced cholesteryl [3H]-oleate deposition at all concentrations tested. However, Bay K 8644, a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Pharmacological Control of Calcium and Potassium Homeostasis

Medical Science Symposia Series • 1995
View 8 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…