Inhibition of cell proliferation by glycerol.

  title={Inhibition of cell proliferation by glycerol.},
  author={John P. Wiebe and C J Dinsdale},
  journal={Life sciences},
  volume={48 16},
The effect of glycerol on proliferation of BHK, CHO, HBL, MCF-7, and human glioma cells was studied. Cell proliferation was significantly decreased in all the cell lines at glycerol concentrations of 2-4% in the culture medium. The inhibition was dose-dependent, complete suppression of proliferation occurring at a glycerol concentration of 4% for the MCF-7 cell line and 6-8% for the BHK, CHO and human glioma cells. Studies on [3H]thymidine incorporation correlate with the effect on cell… CONTINUE READING

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