Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation.

Abstract

Lung cancer is the leading cause of death among all cancers. Non-small cell lung cancer accounts for 80% of lung cancer with a 5-year survival rate of 16%. Notch pathway, especially Notch-1 is up-regulated in a subgroup of non-small cell lung cancer patients. Since Notch-1 signaling plays an important role in cell proliferation, differentiation, and… (More)
DOI: 10.1002/jcb.23184

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@article{Ji2011InhibitionOC, title={Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation.}, author={Xiangming Ji and Zhiwei Wang and Andreea Geamanu and Fazlul H. Sarkar and Smiti Vaid Gupta}, journal={Journal of cellular biochemistry}, year={2011}, volume={112 10}, pages={2773-83} }