Inhibition of cell-cell adhesion and morphogenesis of Dictyostelium by carnitine.

@article{Siu1992InhibitionOC,
  title={Inhibition of cell-cell adhesion and morphogenesis of Dictyostelium by carnitine.},
  author={C H Siu and Prabhjoyt Brar and Irving B. Fritz},
  journal={Journal of cellular physiology},
  year={1992},
  volume={152 1},
  pages={157-65}
}
Carnitine (gamma-trimethylammonium beta-hydroxy-butyric acid) possesses the novel property of preventing cell aggregation elicited by clusterin or by fibrinogen (I.B. Fritz and K. Burdzy, J. Cell. Physiol., 140:18-28 [1989]). In investigations reported here, we show that carnitine also affects cell-cell adhesion in Dictyostelium discoideum, a cellular slime mold whose cells interact in specific and complex manners during discrete stages of development. Two types of cell adhesion systems… CONTINUE READING