• Corpus ID: 28833964

Inhibition of calcium uptake by capsaicin.

@article{Monsereenusorn1985InhibitionOC,
  title={Inhibition of calcium uptake by capsaicin.},
  author={Yongyot Monsereenusorn and Sathapana Kongsamut},
  journal={Research communications in chemical pathology and pharmacology},
  year={1985},
  volume={47 3},
  pages={
          453-6
        }
}
The effects of capsaicin on 45Ca2+ uptake were studied in cultured rat aortic smooth muscle and mouse neuroblastoma cell lines. Capsaicin (up to 300 microM) caused a dose-dependent inhibition of 45Ca2+ uptake both under resting (5 mM K+) and depolarizing (50 mM K+) conditions in both cell lines. These results provide one possible mechanism of action of capsaicin. 
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