Inhibition of brain cholinesterase activity in forest birds and squirrels exposed to aerially applied acephate

  title={Inhibition of brain cholinesterase activity in forest birds and squirrels exposed to aerially applied acephate},
  author={Joseph G. Zinkl and R B Roberts and Charles J. Henny and Diane Lenhart},
  journal={Bulletin of Environmental Contamination and Toxicology},
Inhibition of Brain Cholinesterase Activity in Forest Birds and Squirrels Exposed to Aerially Applied Acephate Joseph G. Zinkl 1,2, Richard B. Roberts 3, Charles J. Henny 4, David J. Lenhart ~ 2Dept. of Clinical Pathology, Univ. of California, Davis, CA 95616, 3Formerly, Pacific Southwest Forest and Range Exp. Sta., U.S. Forest Serv., Berkeley, CA 94701. Presently, Dept. of Entomology, Univ. of Idaho, Moscow, ID 83843 4patuxent Wildlife Research Center, U.S. Fish and Wildlife Service, Corvallis… 

Brain cholinesterase activity and brain and liver residues in wild birds of a forest sprayed with acephate

It is suggested that brain ChE inhibition found after acephate application is a better indicator of exposure than is tissue residue analysis, and is probably due to a metabolite of Acephate that is not detected by the methods used.

The effect of aerial application of Zectran® on brain cholinesterase activity in forest songbirds

Zectran® provides a margin of safety to songbirds exceeding that of the organophosphorus insecticide fenitrothion which is currently used on a widespread operational basis against spruce budworm (Choristoneura fumiferana) in New Brunswick, Canada.

Brain cholinesterase inhibition in forest passerines exposed to experimental aminocarb spraying

This study was carried out in the context of a series of spray trials of a new formulation of aminocarb known as Matacil R 180 Flowable (180F), conducted by the Forest Pest Management Institute, Canadian Forestry Service, primarily to determine efficacy against spruce budworm.

An interlaboratory comparison of data on brain cholinesterase activity in forest songbirds exposed to aerial application of Zectran®

The dosage rate emitted from the airplane was a better predictor of ChE activity in the canopy niches than was volume deposited at ground level, but volume deposited was a more useful predictor for ground birds in most situations.

Effects of fenitrothion on survival, behavior, and brain cholinesterase activity of white‐throated sparrows (Zonotrichia albicollis)

White-throated sparrows were fed six concentrations of dietary fenitrothion for 5 d to determine effects on survival, behavior, and brain cholinesterase (ChE) activity, and level of inhibition was positively related to dietary concentration.

Inhibition of brain acetylcholinesterase activity in songbirds exposed to fenitrothion during aerial spraying of forests

In 1979 and 1980 further areas of forest were sprayed with fenitrothion using the ULV technique and on both occasions sampZes of various avian species were taken to determine any effect on brain acetylcholinesterase (ACHE) activity and provide further information on the distribution of fen itrothion residues in the birds.

Brain acetylcholinesterase activity in forest songbirds exposed to a new method of UULV fenitrothion spraying

Brain AChE inhibition was greater in exposed birds collected after the first 210 g AI/ha spray than after the second one, and variation among species' responses to the sprays is discussed in relation to habitat and foraging preferences.


  • E. Hill
  • Biology
    Journal of wildlife diseases
  • 1988
Overall, whole brain ChE activity varied nearly three-fold among the 48 species represented, but it was usually similar for closely related species, however, some species were statistically separable in most families and some species of the same genus differed as much as 50%.

Inhibition of brain and plasma cholinesterase activity in zebra finches orally dosed with fenitrothion

Zebra finches (Poephila guttata) were given single oral doses of fenitrothion insecticide dissolved in soya bean oil, and brain and plasma cholinesterase (ChE) activities were measured periodically up to 10 d postexposure, with recovery of ChE activity in vivo followed an exponential pattern.

Cholinesterase inhibition in meadow voles (Microtus Pennsylvanicus) following field applications of orthene

Brain acetylcholinesterase activity in field-caught meadow voles was depressed after a field-spray of Orthene® (acephate: acetylphosphoramidothioic acid O,S-dimethyl ester) and short-term recovery was demonstrated and occurred in a time-dependent fashion in 1982.



Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors

Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and

Toxicity of acephate and methamidophos to dark-eyed juncos

The studies indicate that the amount of acephate needed to produce the ChE depression found in other investigations in most dark-eyed juncos exposed to forest applications of insecticide is about one-fifth of the LD50; however, in a few birds the cholinesterase activity may be depressed to near lethal levels.

Studies on combined effects of organophosphates and heavy metals in birds. I. Plasma and brain cholinesterase in coturnix quail fed methyl mercury and orally dosed with parathion

It was found that mercury potentiated the toxicity and biochemical effects of parathion and was directly related to the inhibition of brain cholinesterase in birds fed clean feed and those fed morsodren-treated feed.

GRAMLICH: Forest Insect and Disease Management Evaluation Report. Northeastern Area, State and Private Forestry

  • U.S. Department of Agriculture,
  • 1978