Inhibition of bone marrow-derived dendritic cell maturation by glabridin.

@article{Kim2010InhibitionOB,
  title={Inhibition of bone marrow-derived dendritic cell maturation by glabridin.},
  author={Jee Youn Kim and Jong Soon Kang and Hwan‐Mook Kim and Hwa Sun Ryu and Hyung Sook Kim and Hong Kyung Lee and Yeon Jin Kim and Jin Tae Hong and Youngsoo Kim and Sang Bae Han},
  journal={International immunopharmacology},
  year={2010},
  volume={10 10},
  pages={
          1185-93
        }
}
  • J. Kim, J. Kang, S. Han
  • Published 1 October 2010
  • Biology, Chemistry
  • International immunopharmacology
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References

SHOWING 1-10 OF 35 REFERENCES
Inhibition of phenotypic and functional maturation of dendritic cells by manassantin a.
TLDR
The inhibitory effects of MSA on immune functions of dendritic cells (DCs) are investigated and it is suggested that MSA might be used for the treatment of DC-related immune diseases.
TLR2 modulates inflammation in zymosan-induced arthritis in mice
TLDR
Results show that ZIA is more prolonged than was originally described and involves both the innate and acquired immune pathways, and C3 does not seem to have a major role in this model of joint inflammation.
Glabridin inhibits lipopolysaccharide‐induced activation of a microglial cell line, BV‐2, by blocking NF‐κB and AP‐1
TLDR
It is demonstrated that glabridin inhibits the production of inflammatory mediators in BV‐2 cells and this is mediated, at least in part, by blocking NF‐κB and AP‐1 activation.
Glabridin, an Isoflavan from Licorice Root, Inhibits Inducible Nitric-Oxide Synthase Expression and Improves Survival of Mice in Experimental Model of Septic Shock
TLDR
In vivo anti-inflammatory effect of glabridin suggests a possible therapeutic application of this agent in inflammatory diseases and inhibition of NO production and inducible nitric oxide gene expression is suggested.
Glabridin Suppresses Intercellular Adhesion Molecule-1 Expression in Tumor Necrosis Factor-α-Stimulated Human Umbilical Vein Endothelial Cells by Blocking Sphingosine Kinase Pathway: Implications of Akt, Extracellular Signal-Regulated Kinase, and Nuclear Factor-κB/Rel Signaling Pathways
TLDR
The results indicate that the inhibitory effect of glabridin on ICAM-1 expression might be mediated, at least in part, by inhibiting sphingosine kinase pathway and subsequent inhibition of signaling pathways, including Akt, ERK, and NF-κB/Rel signaling pathway.
T-cell specific immunosuppression by prodigiosin isolated from Serratia marcescens.
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