Inhibition of autophagy by TAB2 and TAB3.


Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 and TAB3), two upstream activators of the TAK1-IKK signalling axis, constitutively interact with each other via their coiled-coil domains… (More)
DOI: 10.1038/emboj.2011.413


Cite this paper

@article{Criollo2011InhibitionOA, title={Inhibition of autophagy by TAB2 and TAB3.}, author={Alfredo Criollo and Mireia Niso-Santano and Shoaib A. Malik and Micka{\'e}l Michaud and Eugenia Morselli and Guillermo Marin͂o and Sylvie Lachkar and Alexander V Arkhipenko and Francis Harper and G{\'e}rard Pierron and J J Rain and Jun Ninomiya-Tsuji and Jos{\'e} Mar{\'i}a de Fuentes and Sergio Lavandero and Lorenzo Galluzzi and Maria Chiara Maiuri and Guido Kroemer}, journal={The EMBO journal}, year={2011}, volume={30 24}, pages={4908-20} }