Inhibition of atherogenesis in LDLR knockout mice by systemic delivery of adeno-associated virus type 2-hIL-10.

Abstract

Atherosclerosis is an inflammatory disease of the arteries. Interleukin-10 (IL-10) is known to be an anti-inflammatory cytokine which might be useful for counteracting the development of atherosclerosis. As long-term systemic cytokine delivery is prohibitively expensive, gene therapy might be a suitable approach. To test this idea, low-density lipoprotein… (More)

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Cite this paper

@article{Liu2006InhibitionOA, title={Inhibition of atherogenesis in LDLR knockout mice by systemic delivery of adeno-associated virus type 2-hIL-10.}, author={Yong Liu and Dayuan Li and Jiawei Chen and Jin Xie and Sarmistha Bandyopadhyay and Dazhi Zhang and Aravind Rao Nemarkommula and Hongmei Liu and Jawahar Lal Mehta and Paul L. Hermonat}, journal={Atherosclerosis}, year={2006}, volume={188 1}, pages={19-27} }