Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis.

@article{Alekseev2014InhibitionOA,
  title={Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis.},
  author={Oleg Alekseev and Kelly Donovan and Jane Azizkhan-Clifford},
  journal={Investigative ophthalmology & visual science},
  year={2014},
  volume={55 2},
  pages={706-15}
}
PURPOSE Herpes keratitis (HK) remains the leading cause of cornea-derived blindness in the developed world, despite the availability of effective antiviral drugs. Treatment toxicity and the emergence of drug resistance highlight the need for additional therapeutic approaches. This study examined ataxia telangiectasia mutated (ATM), an apical kinase in the… CONTINUE READING