Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae

  title={Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae},
  author={Denah M. Appelt and Maria R Roupas and Deana S. Way and Marcus G. Bell and Elizabeth V. Albert and Christine J. Hammond and Brian J. Balin},
  journal={BMC Neuroscience},
  pages={13 - 13}
Chlamydophila (Chlamydia) pneumoniae is an intracellular bacterium that has been identified within cells in areas of neuropathology found in Alzheimer disease (AD), including endothelia, glia, and neurons. Depending on the cell type of the host, infection by C. pneumoniae has been shown to influence apoptotic pathways in both pro- and anti-apoptotic fashions. We have hypothesized that persistent chlamydial infection of neurons may be an important mediator of the characteristic neuropathology… CONTINUE READING


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