Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1

Abstract

The squamous cell carcinoma antigen (SCC Ag) is a tumour-associated protein and a member of theserineproteaseinhibitor (serpin) family. The SCC Ag has been used as a serologic tumour marker for SCC progression, and its elevated serum levels are a risk factor for disease relapse. However, the biologic significance of this intracytoplasmic protein in cancer… (More)
DOI: 10.1054/bjoc.1999.1028

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