Inhibition of antigen-induced proliferation ofT cells from radiation- induced bone marrow chimeras

Abstract

Chimeric BIO.A T cells that had matured in a (BlO.A x B10.Q)F1 environment acquired the ability to respond to poly(Glu'Lys35Phe9) (GL4), an antigen to which the BlO.A mouse is a nonresponder. The response of the chimeric BlO.A T cells was initiated by.GL4 on responder BlO.Q antigen-presenting cells (APC) but not by GL4W on nonresponder BlO.A APC. Similarly… (More)

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