Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts

  title={Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts},
  author={M. Breiner and G. Romalo and H. Schweikert},
  journal={Klinische Wochenschrift},
  • M. Breiner, G. Romalo, H. Schweikert
  • Published 2005
  • Biology, Medicine
  • Klinische Wochenschrift
  • SummaryThe ability of various natural and synthetic steroids (some of which are widely used in clinical practice) to compete with dihydrotestosterone receptor binding in human genital skin fibroblasts was studied. [...] Key Method Binding was assessed in fibroblast monolayers after incubation for 1 h at 37 °C with 2 nM3H-dihydrotestosterone in the presence or absence of increasing concentrations of the steroid to be tested.Expand Abstract
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