Inhibition of alpha-receptor-induced Ca2+ release and Ca2+ influx by Mn2+ and La3+.

Abstract

The influence of Mn2+ and La3+ on alpha-receptor-stimulated Ca2+ movements was examined in arterial smooth muscle of the rabbit aorta. Both cations cause an inhibition of phenylephrine (PE) contractile response which exhibits a different pattern at low and high cation concentrations. At 0.1-1.0 mM inhibition by Mn2+ and La3+ was predominately due to a… (More)

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@article{Deth1981InhibitionOA, title={Inhibition of alpha-receptor-induced Ca2+ release and Ca2+ influx by Mn2+ and La3+.}, author={R C Deth and Christopher J. Lynch}, journal={European journal of pharmacology}, year={1981}, volume={71 1}, pages={1-11} }