Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.

@article{Suryanarayana2004InhibitionOA,
  title={Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.},
  author={P. V. Suryanarayana and Pasupulati Anil Kumar and Megha Saraswat and J. Mark Petrash and G Bhanuprakash Reddy},
  journal={Molecular vision},
  year={2004},
  volume={10},
  pages={148-54}
}
PURPOSE Aldose reductase (AR) has been a drug target because of its involvement in the development of secondary complications of diabetes including cataract. Although numerous synthetic AR inhibitors (ARI) have been tested and shown to inhibit the enzyme, clinically synthetic ARIs have not been very successful. Therefore, evaluating natural sources for ARI potential may lead to the development of safer and more effective agents against diabetic complications. In the present study we have… CONTINUE READING
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Active constituents of Emblica officinalis: Part 1. The chemistry and antioxidative effects of two new hydrolysable tannins, Emblicanin A and B

  • S Ghosal, VK Tripathi, S. Chauhan
  • Indian J Chem
  • 1996
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