Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation.

Abstract

The regulation of neuroendocrine electrical activity and gene expression by glucose is mediated through several distinct metabolic pathways. Many studies have implicated AMP and ATP as key metabolites mediating neuroendocrine responses to glucose, especially through their effects on AMP-activated protein kinase (AMPK), but other studies have suggested that… (More)

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@article{Cheng2008InhibitionOA, title={Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation.}, author={Hui Cheng and Fumiko Isoda and Denise D. Belsham and Charles Vernon Mobbs}, journal={Endocrinology}, year={2008}, volume={149 2}, pages={703-10} }