Inhibition of adrenaline-induced fibrinolysis by alpha-adrenergic blocking agents in the rat.

@article{Sasaki1974InhibitionOA,
  title={Inhibition of adrenaline-induced fibrinolysis by alpha-adrenergic blocking agents in the rat.},
  author={Y. Sasaki and S. Takeyama},
  journal={Japanese journal of pharmacology},
  year={1974},
  volume={24 5},
  pages={
          737-45
        }
}
  • Y. Sasaki, S. Takeyama
  • Published 1974
  • Medicine, Chemistry
  • Japanese journal of pharmacology
    • Abstract The fibrinolysis induced by intraperitoneal injection of adrenaline in the rat was inhibited by prior intraperitoneal injection of very low doses of α-adrenergic blocking agents. For example, 5 μg/kg of phenoxybenzamine or 10 μg/kg of phentolamine was sufficient to prevent almost completely the fibrinolysis induced by 1 mg/kg of adrenaline. These α-blockers also inhibited the fibrinolysis induced by serotonin and bisobrin, but a much higher dosage was required. Phenoxybenzamine did not… CONTINUE READING
    View PDF
    2 Citations
    Background Citations
    1
    2 Citations
    Citation Type

    Citation Type

    Indirect Fibrinolytic Agents
    • 8
    Contribuição ao entendimento da patogenia da sepse
    • 1

    References

    SHOWING 1-4 OF 4 REFERENCES
    Chemical Control of Fibrinolysis-Thrombolysis
    • ALLAN, A.G.E.: Br. J. Haemat
    • 1971
    AND CHOY, W.: Fedn
    • Proc. 23,
    • 1964
    KREN, F. AND VON KAULLA
    • K.N.: Am. J. Med. 31,
    • 1961
    AND ALKJAERSIG
    • N.: J. clin. Invest. 38,
    • 1959