Inhibition of adipocyte inflammation and macrophage chemotaxis by butein.

Abstract

Adipose tissue inflammation has been proposed as a therapeutic target for the treatment of obesity and metabolic disorders such as insulin resistance and type 2 diabetes. Butein, a polyphenol of vegetal origin, exhibits anti-inflammatory effects in macrophages but it was not reported whether butein prevents adipocyte inflammation. Here, we investigated the… (More)
DOI: 10.1016/j.ejphar.2014.05.031

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