Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures.

Abstract

Adenosine kinase (AK) inhibitors potentiate the actions of endogenous adenosine (ADO) and ameliorate cerebral ischemic damage in animal models. The present study examined the effects of the AK inhibitor, 5-iodotubercidin (5-IT) in an in vitro model of neuronal ischemia, specifically, combined oxygen-glucose deprivation of rat cortical mixed neuronal-glial… (More)

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@article{Lynch1998InhibitionOA, title={Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures.}, author={James J. Lynch and Kristen M Alexander and Michael F. Jarvis and Elizabeth A Kowaluk}, journal={Neuroscience letters}, year={1998}, volume={252 3}, pages={207-10} }