Inhibition of Streptococcus mutans 6715 glucosyltransferases by sucrose analogs modified at positions 6 and 6'.

@article{Binder1985InhibitionOS,
  title={Inhibition of Streptococcus mutans 6715 glucosyltransferases by sucrose analogs modified at positions 6 and 6'.},
  author={Thomas P. Binder and John F. Robyt},
  journal={Carbohydrate research},
  year={1985},
  volume={140 1},
  pages={
          9-20
        }
}
Sucrose derivatives modified at position 6 (6-deoxysucrose, 6-thiosucrose, 6,6'-dithiodisucrose, and 6,6'-dideoxy-6,6'-difluorosucrose) were tested as inhibitors of the two Streptococcus mutans 6715 glucosyltransferases. 6-Deoxysucrose was the best inhibitor studied, competitively inhibiting the soluble-D-glucan forming enzyme (GTF-S) and the insoluble-D-glucan forming enzyme (GTF-I) with Ki values one order of magnitude lower than the sucrose Km values. 6-Thiosucrose was also a competitive… 
Inhibition- and acceptor-reaction studies of streptococcus mutans 6715 glucosyltransferases with 3-deoxysucrose, 3-deoxy-3-fluorosucrose, and α-dallopyranosyl β-d-fructofuranoside
Abstract Three new sucrose analogs modified at C-3 have been studied as inhibitors and substrates for the glucosyltransferases (glucansucrases) of Steptococcus mutans 6715. Although none of the
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TLDR
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Effect of carbohydrate fatty acid esters on Streptococcus sobrinus and glucosyltransferase activity.
TLDR
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The Influence of Sucralose on Bacterial Metabolism
TLDR
Sucralose was not utilized by the oral bacteria tested and that the inhibitory effect of sucralose on GTF and FTF was non-competitive and reversible, which further support the concept that Sucralose is non-cariogenic.
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TLDR
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TLDR
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TLDR
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