Inhibition of Renin-Angiotensin System Reverses Endothelial Dysfunction and Oxidative Stress in Estrogen Deficient Rats

@inproceedings{Yung2011InhibitionOR,
  title={Inhibition of Renin-Angiotensin System Reverses Endothelial Dysfunction and Oxidative Stress in Estrogen Deficient Rats},
  author={Lai Ming Yung and Wing Tak Wong and Xiao Yu Tian and Fung Ping Leung and Lai Hang Yung and Zhen Yu Chen and Xiao-Qiang Yao and Chi Wai Lau and Yu Huang},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Estrogen deficiency increases the cardiovascular risks in postmenopausal women. Inhibition of the renin-angiotensin system (RAS) and associated oxidative stress confers a cardiovascular protection, but the role of RAS in estrogen deficiency-related vascular dysfunction is unclear. The present study investigates whether the up-regulation of RAS and associated oxidative stress contributes to the development of endothelial dysfunction during estrogen deficiency in ovariectomized (OVX… CONTINUE READING
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