Inhibition of ROS elevation and damage to mitochondrial function prevents lead-induced neurotoxic effects on structures and functions of AFD neurons in Caenorhabditis elegans.

Abstract

Here we investigated the possible roles of oxidative stress in the formation of decreased thermotaxis to cultivation temperature in lead (Pb)-exposed nematodes Caenorhabditis elagans. Exposure to Pb at the examined concentrations decreased thermotaxis behaviors, and induced severe deficits in the structural properties of AFD sensory neurons. Meanwhile, Pb… (More)

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@article{Wu2012InhibitionOR, title={Inhibition of ROS elevation and damage to mitochondrial function prevents lead-induced neurotoxic effects on structures and functions of AFD neurons in Caenorhabditis elegans.}, author={Qiuli Wu and Peidang Liu and Yinxia Li and Min Du and Xiaojuan Xing and Dayong Wang}, journal={Journal of environmental sciences}, year={2012}, volume={24 4}, pages={733-42} }