Inhibition of RNA viruses in vitro and in Rift Valley fever-infected mice by didemnins A and B.

Abstract

Didemnins, a new class of depsipeptides isolated from a Caribbean tunicate, have been shown to have potent antiviral activity against a broad range of RNA viruses in vitro. Didemnins A and B both protected mice against a lethal challenge of Rift Valley fever virus. 

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