Inhibition of RNA silencing by the coat protein of Pelargonium flower break virus: distinctions from closely related suppressors.

@article{MartnezTurio2009InhibitionOR,
  title={Inhibition of RNA silencing by the coat protein of Pelargonium flower break virus: distinctions from closely related suppressors.},
  author={Sandra Mart{\'i}nez-Turi{\~n}o and C. Cuenca Hern{\'a}ndez},
  journal={The Journal of general virology},
  year={2009},
  volume={90 Pt 2},
  pages={519-25}
}
Viral-derived double-stranded RNAs (dsRNAs) activate RNA silencing, generating small interfering RNAs (siRNAs) which are incorporated into an RNA-induced silencing complex (RISC) that promotes homology-dependent degradation of cognate RNAs. To counteract this, plant viruses express RNA silencing suppressors. Here, we show that the coat protein (CP) of Pelargonium flower break virus (PFBV), a member of the genus Carmovirus, is able to efficiently inhibit RNA silencing. Interestingly, PFBV CP… CONTINUE READING
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