Inhibition of Parietal Cell Acid Secretion Is Mediated by the Classical Epidermal Growth Factor Receptor

Abstract

Epidermal growth factor (EGF) and transforminggrowth factor-α (TGF-α) inhibit gastric acidsecretion both in vivo and in vitro. Previous studieshave indicated that EGF and TGF-α bind to the same EGF/TGF-α receptor. Nevertheless, weand others have previously demonstrated that inhibitionof acid secretion by these growth factors requiresconcentrations of the… (More)
DOI: 10.1023/A:1018845805806

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@article{Joshi1997InhibitionOP, title={Inhibition of Parietal Cell Acid Secretion Is Mediated by the Classical Epidermal Growth Factor Receptor}, author={Virendra Joshi and Gregory S. Ray and James R Goldenring}, journal={Digestive Diseases and Sciences}, year={1997}, volume={42}, pages={1194-1198} }