Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor

@inproceedings{Gentilini2018InhibitionOO,
  title={Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor},
  author={Mar{\'i}a Virginia Gentilini and Ayel{\'e}n Ivana Pesce Viglietti and Paula Constanza Arriola Benitez and Andrea Elena Iglesias Molli and Gloria Edith Cerrone and Guillermo H Giambartolomei and Mar{\'i}a Victoria Delpino},
  booktitle={Front. Immunol.},
  year={2018}
}
Brucella abortus induces an inflammatory response that stimulates the endocrine system resulting in the secretion of cortisol and dehydroepiandrosterone (DHEA). Osteoarticular brucellosis is the most common presentation of the active disease in humans, and we have previously demonstrated that B. abortus infection inhibits osteoblast function. We aimed to… CONTINUE READING