Inhibition of NO2, PGE2, TNF-α, and iNOS EXpression by Shorea robusta L.: An Ethnomedicine Used for Anti-Inflammatory and Analgesic Activity

  title={Inhibition of NO2, PGE2, TNF-α, and iNOS EXpression by Shorea robusta L.: An Ethnomedicine Used for Anti-Inflammatory and Analgesic Activity},
  author={Chattopadhyay Debprasad and Mukherjee Hemanta and Bag Paromita and Ojha Durbadal and K. R. Ananda Kumar and Dutta Shanta and Haldar Pallab Kumar and Chatterjee Tapan and Sharon Ashoke and Chakraborti Sekhar},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
This paper is an attempt to evaluate the anti-inflammatory and analgesic activities and the possible mechanism of action of tender leaf extracts of Shorea robusta, traditionally used in ailments related to inflammation. The acetic-acid-induced writhing and tail flick tests were carried out for analgesic activity, while the anti-inflammatory activity was evaluated in carrageenan-and dextran- induced paw edema and cotton-pellet-induced granuloma model. The acetic-acid-induced vascular… CONTINUE READING


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