Inhibition of MIF leads to cell cycle arrest and apoptosis in pancreatic cancer cells.

@article{Denz2010InhibitionOM,
  title={Inhibition of MIF leads to cell cycle arrest and apoptosis in pancreatic cancer cells.},
  author={Axel Denz and Christian Pilarsky and Daniela Muth and Felix Rueckert and Hans-Detlev Saeger and Robert Gr{\"u}tzmann},
  journal={The Journal of surgical research},
  year={2010},
  volume={160 1},
  pages={29-34}
}
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) is the eighth most common cancer with the lowest overall 5-y relative survival rate. Gene expression profiling of PDAC revealed an overexpression of the macrophage migration inhibitory factor (MIF), a lymphokine involved in cell-mediated immunity and inflammation, as well as in the regulation of cellular… CONTINUE READING