Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina.

@article{Thummel2008InhibitionOM,
  title={Inhibition of M{\"u}ller glial cell division blocks regeneration of the light-damaged zebrafish retina.},
  author={Ryan Thummel and Sean C. Kassen and Jacob E Montgomery and Jennifer M. Enright and David R Hyde},
  journal={Developmental neurobiology},
  year={2008},
  volume={68 3},
  pages={392-408}
}
The adult zebrafish retina possesses a robust regenerative response. In the light-damaged retina, Müller glial cell divisions precede regeneration of rod and cone photoreceptors. Neuronal progenitors, which arise from the Müller glia, continue to divide and use the Müller glial cell processes to migrate to the outer nuclear layer and replace the lost photoreceptors. We tested the necessity of Müller glial cell division for photoreceptor regeneration. As knockdown tools were unavailable for use… CONTINUE READING
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