Inhibition of Inflammatory Cytokine Secretion by Plant-Derived Compounds Inuviscolide and Tomentosin : The Role of NF B and STAT 1

@inproceedings{Abrham2010InhibitionOI,
  title={Inhibition of Inflammatory Cytokine Secretion by Plant-Derived Compounds Inuviscolide and Tomentosin : The Role of NF B and STAT 1},
  author={Galya Abrham and Sara Dovrat and Hanna Bessler and Shlomo Grossman and Uri Nir and Margalit Bergman},
  year={2010}
}
The plant Inula viscosa has been shown to possess many important medicinal benefits, including anti-inflammatory, anti-oxidant, anti-bacterial, and anti-fungal activities, but the plant metabolites that mediate these effects and their mechanism of action are poorly understood. In a previous study, we demonstrated a reduced expression of the p65 subunit of nuclear factor kappa B (NF B) in melanoma cells treated with the purified sesquiterpene lactone compounds, Inuviscolide (Inv) and Tomentosin… CONTINUE READING